G Protein-coupled Receptor Kinase 2 (grk2) Plays a Relevant Role in Insulin Resistance and Obesity
نویسندگان
چکیده
1 Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Complutense University; 28040 Madrid (Spain); 2 CIBER de Diabetes y Enfermedades Metabólicas (CIBERDEM), 3 Departamento de Biología Molecular and Centro de Biología Molecular Severo Ochoa (CSIC-UAM) and Instituto de Investigación Sanitaria Princesa, 28049 Madrid (Spain), 4 Division of Cardiovascular Sciences, Center for Applied Medical Research, University of Navarra, 31008 Pamplona, Spain.
منابع مشابه
G Protein–Coupled Receptor Kinase 2 Plays a Relevant Role in Insulin Resistance and Obesity
OBJECTIVE Insulin resistance is associated with the pathogenesis of metabolic disorders as type 2 diabetes and obesity. Given the emerging role of signal transduction in these syndromes, we set out to explore the possible role that G protein-coupled receptor kinase 2 (GRK2), first identified as a G protein-coupled receptor regulator, could have as a modulator of insulin responses. RESEARCH DE...
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